Spike: Taking up smoking, are you? Harmony: I am a villain, Spike. Hello!

Spike/Harm ,'Help'

Spike's Bitches 49: As usual, I'm here to help you, and I... are you naked under there?

Spike-centric discussion. Lusty, lewd (only occasionally crude), risqué (and frisqué), bawdy (Oh, lawdy!), flirty ('cuz we're purty), raunchy talk inside. Caveat lector.

Jessica - Jan 30, 2024 1:29:26 pm PST #8014 of 8059
If I want to become a cloud of bats, does each bat need a separate vaccination?

I was the same clothing size for my entire twenties no matter how much weight I gained. Then after I had kids my body changed shape/size so completely I had to replace my entire wardrobe. There's just such a huge overlap between Womens' Clothing Sizes Are Bullshit and Bodies Are Weird Sometimes that I couldn't even begin to predict what would happen if I lost a bunch of weight now.

meara - Jan 31, 2024 9:05:38 am PST #8015 of 8059

Yeah—I’ve also lost 60 pounds and gone from a 14 to a 4(!) now. But I would say that I was mostly wearing the bigger of my 14s and so on, and still could wear 12s for a long time. The last 10 pounds or so have gone from 8 to 4, so there’s definitely more change in tiny increments there. (Also my waist is still not that small but I have no ass anymore so things fit around my hips…I’d rather have an ass?)

Also definitely size inflation going on—I have a size 8 skirt from college that still barely fits, even though I’m 5 pounds less than I was then…

Dana - Jan 31, 2024 10:10:35 am PST #8016 of 8059
"I'm useless alone." // "We're all useless alone. It's a good thing you're not alone."

meara, do you mind if I ask you about the drug you're on?

meara - Jan 31, 2024 10:35:50 am PST #8017 of 8059

Dana, it’s an experimental drug—I’m on a trial so could either be on placebo (lol totally not), semaglutide, a new drug called cagrilinitide, or a combo of those two (most likely what I’m on!) called CagriSema. Cagrilinitide works on a different thing than Semaglutide does.

For me it’s been amazing—I did have some pretty bad nausea when I first tried to increase the dose, but since then it’s rarely been an issue and more an issue of “trying to eat ENOUGH”. And some constipation (because it slows down your whole digestive system). I’ve not eaten as much protein as I should’ve, so know I’ve lost more muscle than ideal. But it’s been super easy, for the first time ever in my life. At this point they lowered my dose because I’ve lost all the weight I need or want to, and they don’t want me to lose more.

I’m a little worried that when the trial is over (July) I will promptly gain back all the weight but crossing my fingers that I can either get on a follow up study or manage to pay for a maintenance dose of Ozempic or similar.

If anyone is interested in a trial I highly recommend searching clinicaltrials.gov for obesity or weight loss indications and seeing if anything is enrolling! My sister found an academic study that has had her on Semaglutide, and my brother found a cagrisema vs Semaglutide study that he just started on (so no placebo!).


meara - Jan 31, 2024 11:00:32 am PST #8018 of 8059

So for instance if any of you meet the criteria and there’s a location listed near you, you can contact the number to get connected (or if it specifies the name of the place near you, you can call them directly)



Dana - Jan 31, 2024 11:03:21 am PST #8019 of 8059
"I'm useless alone." // "We're all useless alone. It's a good thing you're not alone."

Interesting, meara. Thanks.

JenP - Jan 31, 2024 11:24:26 am PST #8020 of 8059

I would love to get on one of those or something already approved BECAUSE of the slow down your digestive system effect - losing thirty would be great, but reducing my trips to the loo on some days would be HEAVEN. I'd pay cash money for anything that slowed my gut's roll. Why have I dragged my feet seeing the doctor I need to see about this? Jesus, Jennifer.

EpicTangent - Feb 11, 2024 11:42:40 pm PST #8021 of 8059
Why isn't everyone pelting me with JOY, dammit? - Zenkitty

Yesterday was the gathering for my friend, Patrick. I had a pleasant time and chatted with some lovely people who knew him from different places than I did so we had never met before. It was completely unstructured, no one even said any, like, "final remarks", which would have had me feeling like I was lacking closure. But they had a display they put together to give to his folks, which included 5 or 6 photos that I contributed and a place to write messages. So I decided that getting to say one last goodbye was perfectly nice closure. Turns out it was pancreatic cancer. So, as usual, cancer can fuck right off.

erikaj - Feb 12, 2024 3:13:10 pm PST #8022 of 8059
If Scooby Doo taught me anything, it's that the only thing to fear is real-estate developers.Lisa Simpson

I feel as though I've sincerely gotten mansplained, because somebody has finally hit on some of my expertise. To wit: "You've heard of sarcasm, right?"(Although when it comes to abled people understanding ableism...well, let's just say, at times, it does not hurt to start slowly.) I could have posted "No! Enlighten me." and ended up in a total chatbot-ish loop.

EpicTangent - Feb 12, 2024 5:38:33 pm PST #8023 of 8059
Why isn't everyone pelting me with JOY, dammit? - Zenkitty

Stay strong, Erika. Probably not worth the agita to engage with that type.