3x12

Dean: This is pretty wild, right? I mean it's like they're coming straight for us. They've never done that before. Like we've got a contract on us. You think it's 'cause we're so awesome? I think it's 'cause we're so awesome.

...

Ruby: Does anyone have a breath mint? Some guts splattered into my mouth while I was killing my way in here.

...

FBI Agent Henricksen: Sam and Dean Winchester were in the chopper when it caught on fire. Nothing's left. Can't even identify 'em with dental records. Rest in peace, guys.

S1, Hell House

Sam: I was the one that called them and told them I was a Hollywood producer.
Dean: Well I was the one that put the dead fish in their back seat.

Probably too long.

S2 2x13 Sam: I don’t know, Dean, I just, uh, I wanted to believe so badly. It’s so damned hard to do this, what we do. All alone, you know. And…there’s so much evil out in the world, Dean, I feel like I could drown in it. And when I think about my destiny, when I think about how I could end up…

Dean: Yeah, well, don’t worry about that, all right? I’m watching out for you.

Sam: Yeah, I know you are. But you’re just one person, Dean. And I needed to think that there was something else watching too, you know? Some higher power, some greater good. And that maybe I…

Dean: Maybe what?

Sam: Maybe I could be saved.

3x10

Dean: He's the one who let mom die! Who wasn't there for Sam, I always was! It wasn't fair! I didn't deserve what he put on me and I don't deserve to go to Hell!

S2 2x13 Dean: There's no higher power, there's no God. I mean, there's just chaos, and violence, and random unpredictable evil that comes out of nowhere and rips you to shreds.

3x08 Young Dean: First thing you have to know is we have the coolest dad in the world. He's a superhero.

3x8

Dean: You fudging touch me agian I'll fudging kill you!

3x11 Sam and Dean: (In unison): Right, you're a mind reader. Cut it out, Sam... Sam! You think you're funny but you're being really, really childish! - Sam Winchester wears makeup. Sam Winchester cries his way through sex. Sam Winchester keeps a ruler by the bed and every morning when he wakes up..... Okay, enough!

S3, Dream a Little Dream of Me

Dean: You're like a father to me!

Demon Dean: The music? That's Dad's. The car, the jacket? All Dad's.

Dean: I don't want to die. And I don't want to go to hell.
Sam: Then we'll find a way to save you.
Dean: Okay, good.

3x08:Dean: What'd Bobby say?

Sam: Uh, that we're morons.

THIS WILL GET MY VOTE FOREVER AND EVER.