S4, R1, Bracket #1/4:

Sam: I'm infected with demon blood. You've been to Hell. --The other one is so oft-quoted it's become annoying.

Castiel: You should show me some respect. I dragged you out of hell. I can throw you back in.--I like the shivery delivery (sorry).

Dean: Sam loves research. He does. He keeps it under his mattress, right next to his KY. It's a sickness, it is.-- Well, really, no contest, right?

Alastair: Don't you recognize me? Oh, I forgot -- I'm wearing a pediatrician.--Just an awesome intro.

S4, R1, Bracket #2/4:

Dean: On November 2nd 1983, don't get out of bed. No matter what you hear, or what you see. Promise me you won't get out of bed.--Oh Dean, you can't save your mother. Or avert everything that's going to pile down upon your family. but I know you had to try.

Bobby: Solid iron. Completely coated in salt. One hundred percent ghost-proof.
Sam: You built a panic room?
Bobby: (defensively) I had a weekend off. -- Yeah, Bobby!

Dean: Y'know, I finally get why you and Dad butted heads so much. You two are practically the same person. I mean, I worshiped the guy, I dressed like him, I acted like him. I listened to the same music. But you are more like him than I will ever be. And I see that now.
Sam: I'll take that as a compliment.
Dean: You take it any way you want. --Bitter brotherhood.

Dean: Us? Right. And that Sam, that is exactly why our lives suck. I mean, come on, we hunt monsters! What the hell?! I mean, normal people, they see a monster, and they run. But not us, no, no, no, we -- we search out things that want to kill us. Yeah? Huh? Or eat us! You know who does that? Crazy people! We...are insane! You know, and then there's the bad diner food and then the skeevy motel rooms and then the truck-stop waitress with the bizarre rash. I mean, who wants this life, Sam? Huh? Seriously? Do you actually like being stuck in a car with me eight hours a day, every single day? I don't think so! I mean, I drive too fast. And I listen to the same five albums over and over and over again, a-and I sing along. I'm annoying, I know that. And you --you're gassy! You eat half a burrito, and you get toxic! I mean, you know what? You can forget it. --Tell us what you really feel, Dean.

S4, R1, Bracket #3/4:

Dean: You can take your peace, and shove it up your lily-white ass. 'Cause I'll take the pain, and the guilt, I'll even take Sam as is. It's a lot better than bein' some Stepford Bitch in paradise!--Oh, Dean.

Sam: Dude, you're confusing reality with porn again. --ever the realist when it comes to your brother.

Dean: Angel or not, I will stab you in the face. -- I believe he'd at least try.

Dean: If He doesn't exist, fine. Bad crap happens to good people. That's how it is. And no rhyme or reason, just random horrible, evil. I get it. Okay? I can roll with that. But if He is out there, what's wrong with Him? Where the hell is He while all these decent people are getting torn to shreds? How does He live with Himself? You know, why doesn't He help?-- I have nothing to add to that.

S4, R1, Bracket #4/4:

Sam: I tried everything. That's the truth. I tried opening the Devil's Gate. Hell, I tried to bargain, Dean, but no demon would deal, all right? You were rotting in Hell for months. For months, and I couldn't stop it. So I'm sorry it wasn't me, all right? Dean, I'm sorry. --The delivery kills me, every time.

Dean: There's Sam Girls and Dean Girls and...What's a slash fan? Sam: As in Sam slash Dean together. Dean: Like together, together? They do know we are brothers right?--although I love the other quote like burning, this one is superior.

Bobby: You stupid, stupid son of a bitch! Well, boo hoo! I am so sorry your feelings are hurt, princess! Are you under the impression that family's supposed to make you feel good, make you an apple pie, maybe? They're supposed to make you miserable! That's why they're family!--Bobby doesn't pull punches, man.

Castiel: Uriel's the funniest angel in the garrison. Ask anyone.--no contest.

For your viewing pleasure, a couple of behind-the-scenes pics from 5.10. Can you tell what's different between this picture and this one?

Can you tell what's different between this picture and this one?

Jared only looks back in concern when it's actually Jensen playing Dean?

Yeah, I was going to say in the first picture it's Jensen's stunt double, not Jensen .

Season 4, Round 1, Bracket #1/4

Castiel: I'm the one who gripped you tight and raised you from perdition. -- And, lo, Cas was awesome.

Castiel: You should show me some respect. I dragged you out of hell. I can throw you back in. -- This was almost hard because I like original flavor Ruby way more but the Al Gore line was pretty awesome. But Castiel is a BAMF. And I am showing him some respect.

Chuck: I am the prophet Chuck! -- This is the first vote where I am ambivalent.

Alastair: Don't you recognize me? Oh, I forgot -- I'm wearing a pediatrician. -- He chewed some scenery, yes, but Alastair was kinda my favorite baddie. He creeped me out.

Season 4, Round 1, Bracket #2/4

Chief: Oh, you ain't been had till you been had by The Chief. Oh, and before we get started, what's your safe word? -- Dear Show, thank you for making my subtexty jokes DOMtextual.

Bobby: (defensively) I had a weekend off. -- Bobby is the man!

Dean: Y'know, I finally get why you and Dad butted heads so much. You two are practically the same person. I mean, I worshiped the guy, I dressed like him, I acted like him. I listened to the same music. But you are more like him than I will ever be. And I see that now.

Sam: I'll take that as a compliment.

Dean: You take it any way you want. -- Hello, broken boys. I apologize but I like you this way.

Young Mary Winchester: I want a family. I wanna be safe. You know the worst thing I can think of, the very worst thing, is for my children to be raised into this like I was. -- It was a weak Dean quote. I am voting against this as soon as I can with a clear conscience.

Season 4, Round 1, Bracket #3/4

Alastair: (coughing) Something caught in my throat. (pause) I think it's my throat. -- Seriously, Alastair was an awesome baddie.

Sam: Dude, you're confusing reality with porn again. -- HEE!!

Dean: Angel or not, I will stab you in the face. -- That's the spirit, Dean!

Dean: If He doesn't exist, fine. Bad crap happens to good people. That's how it is. And no rhyme or reason, just random horrible, evil. I get it. Okay? I can roll with that. But if He is out there, what's wrong with Him? Where the hell is He while all these decent people are getting torn to shreds? How does He live with Himself? You know, why doesn't He help? -- Oh, Dean. You make a fine point here.

Season 4, Round 1, Bracket #4/4

Sam: I tried everything. That's the truth. I tried opening the Devil's Gate. Hell, I tried to bargain, Dean, but no demon would deal, all right? You were rotting in Hell for months. For months, and I couldn't stop it. So I'm sorry it wasn't me, all right? Dean, I'm sorry. -- Sam tried things that would destroy the world to get Dean back. And failed. This hurts me. Badly.

Dean: There's Sam Girls and Dean Girls and...What's a slash fan?

Sam: As in Sam slash Dean together.

Dean: Like together, together? They do know we are brothers right? -- They know. They don't care. Oh, Show. Sometimes you make me more uncomfortable than the people who write happy John/Dean.

Bobby: You stupid, stupid son of a bitch! Well, boo hoo! I am so sorry your feelings are hurt, princess! Are you under the impression that family's supposed to make you feel good, make you an apple pie, maybe? They're supposed to make you miserable! That's why they're family! -- While I really want to know what the deal is with sexing Sam = death, this was just ... true.

Castiel: Uriel's the funniest angel in the garrison. Ask anyone. -- Just makes me laugh.

Yeah, it's Todd. Can't fool you guys. I looked at that and thought, it's running. From here to there. He needs a stuntie for running?

Maybe Jensen was getting interviewed or made up or was otherwise busy and Jared wanted a run-through of the blocking ?

Season 4, Round 1, Bracket #1/4:

Castiel: I'm the one who gripped you tight and raised you from perdition. - such a killer intro line

Ruby: This body is 100% socially conscious. I recycle. Al Gore would be proud.. - could make you like Ruby for the snark (what might have been)

Chuck: I am the prophet Chuck! - cause it rocks

Chuck: Well there is only one explanation. Obviously I'm a God. A cruel, cruel capricious god. - foreshadowing!

Season 4, Round 1, Bracket #2/4:

Dean: On November 2nd 1983, don't get out of bed. No matter what you hear, or what you see. Promise me you won't get out of bed. - Dean trying to make things right

Bobby: Solid iron. Completely coated in salt. One hundred percent ghost-proof.
Sam: You built a panic room?
Bobby: (defensively) I had a weekend off. - Of course this is what Bobby does in his free time

Dean: Y'know, I finally get why you and Dad butted heads so much. You two are practically the same person. I mean, I worshiped the guy, I dressed like him, I acted like him. I listened to the same music. But you are more like him than I will ever be. And I see that now.
Sam: I'll take that as a compliment.
Dean: You take it any way you want. - What Dean says is so true and it also illustrates his disillusionment with his father.

Young Mary Winchester: I want a family. I wanna be safe. You know the worst thing I can think of, the very worst thing, is for my children to be raised into this like I was. - poor poor Mary

Season 4, Round 1, Bracket #3/4:

Dean: You can take your peace, and shove it up your lily-white ass. 'Cause I'll take the pain, and the guilt, I'll even take Sam as is. It's a lot better than bein' some Stepford Bitch in paradise! - Go Dean!

Sam: Dude, you're confusing reality with porn again. - brothers.. . .

Dean: Brother! I have been re-hymenated. And the dude will not abide! -see above

Wes: Aren't you the guys from the health department?
Sam: Yeah. And florists on the side.
Dean: Plus FBI. And on Thursdays, we're teddy bear doctors. - love this

Season 4, Round 1, Bracket #4/4:

Sam: I tried everything. That's the truth. I tried opening the Devil's Gate. Hell, I tried to bargain, Dean, but no demon would deal, all right? You were rotting in Hell for months. For months, and I couldn't stop it. So I'm sorry it wasn't me, all right? Dean, I'm sorry.

Dean: There's Sam Girls and Dean Girls and...What's a slash fan?
Sam: As in Sam slash Dean together.
Dean: Like together, together? They do know we are brothers right?

Bobby: You stupid, stupid son of a bitch! Well, boo hoo! I am so sorry your feelings are hurt, princess! Are you under the impression that family's supposed to make you feel good, make you an apple pie, maybe? They're supposed to make you miserable! That's why they're family!

Castiel: Uriel's the funniest angel in the garrison. Ask anyone. - I can't wait for more Castielisms from season 5.