On a completely separate note, I’ve been considering trying microdosing semiglutides for a few months to see how it goes and am curious if anyone else has done so or has any thoughts on it here. I’m not interested in full doses because I can’t handle extreme nausea and other GI issues, but I’m curious if a microdose might reduce cravings, have sleep benefits, help with me PCOS and diabetes risk etc. I already do strength-training twice a week, which I hope would offset any muscle loss.

My personal experience was with Ozempic, and I can't say when in the dosing ramp up the food noise issue got better, but it wasnt right away. The effect disappeared when I went off of it.

I'm now on the Wegovy pill and did not notice anything at all on the lowest dose (no ill or positive effects), and I start the second month's ramp up dose tomorrow. Won't be at full dose until the fourth month.

I hadn't heard of microdosing GLP-1, but I also didn't suffer from nausea on the injectable or the pills (so far, anyway). But the low dose pill has not had any effect on the "craving" aspect, if that's a useful data point.

Thanks, Jen!

I switched from once a week to halving the dose for twice a week instead to lessen side effects. I was told you could divide the weekly dose into as many days as convenient. The only issue I have had is that I really can't eat at night unless I want to suffer. Overeating isn't an issue because often by the time I have prepared the food, I already have lost interest.