Ibuprofen works okay for me and acteminophen works great for fevers for me. But really, naproxen is the one true OTC painkiller. Is it killing my liver or my kidneys?

Not a big opioid person. When I had demerol after the c-section it just made me sleepy.

Meara, go easy on yourself.

I'm pretty sure ibuprofen is only dangerous for your kidneys if you already have a kidney condition, or indicators that you're likely to develop one. (Not a doctor but used to work on End Stage Renal Disease programs for Medicare.)

Go Theodosia!

Ibuprofen was my drug of choice back when I had cramps. Now that I'm past that, it seems to work for headaches and such. The only thing that helped when my knees were acting up seemed to be CBD oil.

I've had opioids after minor surgery, and they seemed to do their job. When I stopped hurting I stopped taking them. But clearly, different people react differently to various meds.

As a person with migraines, I depend on Ibuprofen (makes it easier and more tolerable, does not take away all of the pain).

Naproxen is my favorite, also.

I had prescriptions for Percocet and Ibuprofen after my back surgery. After the first week or so, I'd take one Percocet first thing in the morning (to get through the day) and one last thing at night (to help me sleep), with Ibuprofen as needed during the day. I found it a good balance between management of mild pain and concerns about addiction. (Obviously, your pain may vary.)

I find naproxen only slightly more effective than Tylenol. Oh, how I miss being able to tolerate ibuprofen; it gives me massive feedback headaches now.

Naproxen is my go to for the long-lastingness, but for breakout pain that that doesn't touch, I find Tylenol more immediately effective. Once I remember that there are things you can take for pain, which usually takes me a while.

I find Tylenol more immediately effective

Lies! They are evil placebos!

Seriously, I think it's interesting how different people respond to different meds. I find that shit fascinating.

I generally take Naproxen for pain of all types because I have it handy to ward off incoming migraines. Never touch Tylenol these days because it doesn't help avert them, only numbs the pain a bit once they hit (and if I'm going to slowly kill my liver, it's at least going to be with something that leaves me migraine-free).

My doctor told me to take Ibuprofen for tendon and joint pain, but it never seems to occur to me that I can actually do that when there's a bottle handy nearby. Happy to say tendonitis in my ankle has stopped bothering me since I lost some weight though. (The one thing an episode of depression is good for!)