He hangs out in doorways and in her closet.

Sounds like a territorial thing. He probably feels dislike/distrust/fear towards her by this point. (All basically the same emotion, to a cat.) I'd suggest stopping with the spray bottle, and trying to avoid giving the cat reason to fear being stepped on/shoved/sprayed - just giving him a little space. Can he be separated from her, even for a while, and then reintroduced slowly with treats and happy things, like you'd do for two cats who were fighting?

Also playing more. A LOT more. I had no idea you tried the water bottle before or I would not have recommended it. It only works in the short term. The loud OW thing is doing what another cat would do--give a distress cry, so the cat knows he is hurting you.

If it's territorial, I agree, some safe places for the kitty will help a lot.

I've seen those tunnel things, but he is too big for most of them. I'm sure that she does say "Ow!" and I make a big deal any time he acts like he'll nip, but it also comes with water and cussing.Because he draws blood, a lot. We don't have a lot of space, although more than in Manhattan MCFH, at just over 1000 sq. feet, but we also don't have a woman setting up genius cat window boxes, either, although being up is more Tina's thing than Rocky's. Rocky loves boxes and paper bags.

It doesn't have to be a fancy window box, especially if Rocky prefers a ground-level condo. A cardboard box of the size/type he prefers, in an area where he likes to be, with a towel in it that smells like him, is all you need.

With a tiny narrow kitchen and three cats, I'm having some space issues. They won't eat in there if I'm in there moving around, even though they have never been stepped on. I've taken to feeding them under the dining room chairs, one cat to a chair. They seem to feel safer there. Luckily I never have visitors.

Just as Gregory House seemed always to go for the Lupus diagnosis, these days I am forever asking about pet utis.

This article talks about utis and their effect on cats.

I am Cranktina of the Cranktown Crankstons right now.

My sister! For, lo! I am Cranketta.

I'll second the OW! and the playing more. I've also had to be firm with friends who tolerate play biting. I've seen it escalate all too quickly.

I will use the laser pointer sparingly, as it can get Finn into a good house-long run and help get him good and mellow. I'm careful not to run him into anything, and I always follow laser play with something he can catch and "kill."

I am Cranktina of the Cranktown Crankstons right now.

My sister! For, lo! I am Cranketta.

When is our family reunion? For, lo! I am Crankinbelle.

When is our family reunion? For, lo! I am Crankinbelle

I'm Crankanna, but too cranky to share space with anyone else. So, no reunion for me.

I am Cranketta

Sistah. [insert Crankston's secret family handshake...which no doubt includes a severely scrinchy face]

Thankfully, the employee in question finally took her dog to the vet and it is clear that he sustained the injuries she described. One of the wounds had to be stitched...which is unusual for punctures...so it is a good thing she took my advice.

Now, it's up to the owner to decide if she wants to pay the vet bill and explain to the client that we don't have any proof of what actually happened.

Feh.